Scientific research shows that the interaction of specific genes with the microorganisms that live in our intestines (our gut microbiome) could influence our ability to think, learn, and remember (cognitive durability).
The i-Forget pilot study advances research on this connection between our gut and cognitive durability related to Alzheimer’s disease.
More than 50 Canadians with a family history of Alzheimer’s disease and their live-in partners are participating in our pilot study. They have contributed biological samples for genetic testing and completed a health survey and cognitive test.
By analyzing the data from our participants, we will determine if there are potential links between genetic factors, health and lifestyle, and the gut microbiome.
Following a successful pilot, we will recruit thousands of Canadian study participants to generate the large dataset researchers need to identify the biological markers that could uncover new Alzheimer’s prevention strategies.
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The gut microbiome may be a modifiable risk for future brain performance.
Our pilot study focuses on a small number of participants. It builds on the findings of other recent scientific studies, and will determine whether there is a difference in gut microbiome composition due to family history or inherited genetics.
The participants' live-in partners (who don't have a family history of Alzheimer's disease) serve as a control group.
The lead scientist of this study is Dr. Brent Zanke MD, PhD Molecular Genetics.
Other scientific collaborators include:
Your information is safe and confidential
The Veritas IRB Research Ethics Approval Board in Canada has approved the i-Forget discovery initiative. This approval assures you we have met health-industry standards for personal information and privacy security.
No information that may directly identify participants personally will be released to i-Forget researchers.
All data is stored electronically in an encrypted form, with access safeguards consistent with those protecting personal health information.
All data is associated with a unique personal study ID number. The electronic form is stored in an encrypted form according to Canadian personal health information standards, PIPEDA.
Canadian charity The Durable Mind Collective (DMC) funds the i-Forget research study. Personal donations and in-kind contributions from genetic sequencing service providers have made the pilot study possible. DMC and i-Forget have no ties to any commercial interests, such as pharmaceutical companies, dietary supplements, or probiotic marketers.
We want to hear from you if you have questions about the study or are interested in partnering with us.
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